01537nas a2200205 4500008004100000245005100041210005100092260001700143300001000160490000600170520095900176653002601135653001601161653002301177100002401200700002901224700002201253700002101275856003501296 2017 eng d00aIn vitro Antidiabetic Activity of Sulforaphane0 aIn vitro Antidiabetic Activity of Sulforaphane cOctober 2017 a47-490 v33 a
Background: Sulforaphane is mainly found in cruciferous vegetables. It is a glucosidal prodrug with many pharmacological activities like anti oxidant, anti ulcer, anti viral etc. The present work aims the screening of in vitro anti diabetic activity of Sulforaphane from broccoli extract. Method: The Hypoglycemic activity was performed with amylase inhibition assay by using chromogenic DNSA method. In this percentage inhibition of analyte was compared with that of control to conclude the proved anti diabetic activity. Result: Majority analyte concentration of 500μg exhibits significant inhibition of amylase enzyme which reflects potent anti diabetic effect. Conclusion: Despite of many adverse effects and short shelf life of present drugs here is a proved possibility of anti diabetic effect was found in Sulforaphane from broccoli extract.
10aAntidiabetic activity10aDNSA method10aGlucosidal prodrug1 aBasha, Shaik, Chand1 aBabu, Komaragiri, Rajesh1 aMadhu, Medabalimi1 aGopinath, Chakka uhttp://fulltxt.org/article/353