02166nas a2200253 4500008004100000245007200041210006900113260001900182300001000201490000600211520140600217653000901623653000901632653000701641653002001648653002501668653000801693100002501701700002801726700003601754700003201790700003001822856006001852 2017 eng d00aIn vitro Antioxidant Activity of Extracts of Psidium guajava Leaves0 aIn vitro Antioxidant Activity of Extracts of Psidium guajava Lea cSeptember 2017 a50-540 v33 a

Background: The incidence of diabetes is increasing rapidly in world wide. It produces disturbances in the metabolism of carbohydrate, protein, and lipid. The reports prove that the various oxidative reactions are responsible for the various disorders like diabetes, cancer, aging etc. Evidences recommended that the natural medicines originating from plant source may represent a culturally relevant complementary treatment for diabetes. The present study aims to investigate the antioxidant activity of P. guajava leaves in an in vitro model of various extracts such as aqueous, ethanol and methanol. Method: The scavenging activity of DPPH, reducing power assay, NO, H2O2 and SOD is determined. Results: The results of the present study, proves all the three extracts which have an antioxidant activity in a dose dependent manner (250, 500, 750, 1000, 1500 μg/ml). The ethanolic extract of P. guajava leaves which have high activity when compared to the other two extracts. Conclusion: All the three extracts of P. guajava leaves have an antioxidant activity in an in vitro model. Among the various extracts, the ethanolic extract has a high activity. Further studies are needed for compound identification and its action in an in vivo model

10aDPPH10aH2O210aNO10aPsidium guajava10aReducing power assay10aSOD1 aManikandan, Ramasamy1 aAnand, Arumugam, Vijaya1 aRengaraj, Rengasamy, Lakshminar1 aVinayakamoorthi, Puthamohan1 aRamalingam, Radhakrishnan uhttp://ptbreports.org/article/2017/3/3/105530ptb2017310