02035nas a2200229 4500008004100000245006800041210006800109260001900177300001000196490000600206520134800212653002401560653001901584653002901603653000801632653001001640653002601650100002401676700003701700700002301737856004501760 2015 eng d00aInfluence on Quality of Life Among Patients with Hypothyroidism0 aInfluence on Quality of Life Among Patients with Hypothyroidism c27th Feb, 2015 a24-260 v13 a

Aim: The study is to analyze the influence of quality of life with the patients suffering from hypothyroidism. Methods: This is a prospective observational study conducted for 6 months at endocrinology OPD of a tertiary care teaching hospital, India. Patients diagnosed with hypothyroidism were included in our study. Parameters such as TSH, tT3 and tT4 levels were monitored and their QOL were measured by using short form 36 (SF-36) questionnaires during their baseline and review visit. This study was approved by the human ethical committee. Influence of thyroid parameters over QOL scales were measured statistically using stepwise multiple linear regression and paired ‘t’ test was used to measure the significant difference with the treatment. Results and Discussion: A total of 13 patients met the inclusion criteria of our study among 30 patients irrespective of gender, significant change in thyroid parameter with treatment with L-thyroxine was observed with TSH (p=0.0169*) and further the influence of QOL have shown some significant values, which shows the need for considering the QOL while treating hypothyroidism. Conclusion: The influence of hypothyroidism on the quality of life was observed significantly correlating with few QOL subscales.

10aCorrelating factors10aHypothyroidism10aPatient reported outcome10aQOL10aSF-3610aThyroid function test1 aParuchuri, Sireesha1 aBalasubramanian, Ganesh, Pandian1 aNagula, Parashuram uhttp://ptbreports.org/article/2015/1/1-4