@article {31, title = {In vitro Antidiabetic Activity of Sulforaphane}, journal = {Pharmacology, Toxicology and Biomedical Reports}, volume = {3}, year = {2017}, month = {October 2017}, pages = {47-49}, type = {Short Communication}, chapter = {47}, abstract = {

Background: Sulforaphane is mainly found in cruciferous vegetables. It is a glucosidal prodrug with many pharmacological activities like anti oxidant, anti ulcer, anti viral etc. The present work aims the screening of in vitro anti diabetic activity of Sulforaphane from broccoli extract. Method: The Hypoglycemic activity was performed with amylase inhibition assay by using chromogenic DNSA method. In this percentage inhibition of analyte was compared with that of control to conclude the proved anti diabetic activity. Result: Majority analyte concentration of 500μg exhibits significant inhibition of amylase enzyme which reflects potent anti diabetic effect. Conclusion: Despite of many adverse effects and short shelf life of present drugs here is a proved possibility of anti diabetic effect was found in Sulforaphane from broccoli extract.

}, keywords = {Antidiabetic activity, DNSA method, Glucosidal prodrug}, doi = {10.5530/PTB.2017.3.9}, url = {http://fulltxt.org/article/353}, author = {Shaik Chand Basha and Komaragiri Rajesh Babu and Medabalimi Madhu and Chakka Gopinath} }