@article {139, title = {Analysis of Antimicrobial Medication Consumption in Intensive Care Unit, North West (Tabuk) Region Hospitals, Saudi Arabia}, journal = {Pharmacology, Toxicology and Biomedical Reports}, volume = {5}, year = {2019}, month = {August 2019}, pages = {119-123}, type = {Research Article}, chapter = {119}, abstract = {

Objectives: This article describes antimicrobial medication use among different age groups and the cost associated with it in intensive care units at North West (Tabuk) hospitals, Saudi Arabia. The aim of this study to explore the antimicrobial medication use in intensive care units at North West Region Hospitals, Ministry of Health, Saudi Arabia. Methods: It is a 12-month antimicrobial drug use by intensive care units at North West region hospitals which included critical care for adults, pediatrics and neonates. The medications selected by Central Antibiotics committee at MOH as part of the National Antimicrobial Stewardship program. The consumption was driven from pharmacy database and calculated based on off standard unit of antimicrobials per hospital. The antimicrobials consisted of antibacterial drugs, antifungal and antiviral medications. The cost of antimicrobial consumption was calculated by using the Ministry of Health National Cost database. All cost used were as US currency. Results: The total number of antimicrobial standard units were (14,305) and average (2,861) per hospital. The highest drug consumption was Ceftriaxone 1 gm injection (2724) followed by Imipenem 500 mg injection (1251) and Vancomycin 500 injection (1165). The total cost of Antimicrobial consumption was (53,884.95 USD) and (10,777 USD) per each hospital. The highest cost medication consumption from Adults critical care 73.42\% (39,562.33 USD) followed by pediatrics critical care 18.15\% (9,779.93 USD) and Neonates critical care 8.43\% (4,542.68 USD). The highest medication cost was very broad-spectrum antibiotics like Meropenem, Imipenem and Ceftriaxone. It consumed more than 50\% of the cost burden. Conclusion: This study is the first in Saudi Arabia, Gulf and Middle East countries. Health system pharmacist leaders are targeting to implement the antimicrobial stewardship program and National Drug Utilization Evaluation system to control unnecessary medication expenditure and prevent misuse of medicines.

}, keywords = {Knowledge, Medications, Ministry of Health, Patient, Saudi Arabia}, doi = {10.5530/PTB.2019.5.22}, author = {Yousef Ahmed Alomi and Abeer Hussin Almasoudi and Ghormallah Abdullah Alghamdi and Samira Ali Asiri} } @article {141, title = {Analysis of Antimicrobial Medications Consumption in Inpatient Units at North West (Tabuk) Region Hospitals, Saudi Arabia}, journal = {Pharmacology, Toxicology and Biomedical Reports}, volume = {5}, year = {2019}, month = {August 2019}, pages = {130-134}, type = {Research Article}, chapter = {130}, abstract = {

Background: This article aims to explore antimicrobial medication consumption and related cost among different age groups in inpatient units at North West Region Hospitals, Ministry of Health, and Saudi Arabia. Objectives: To explore the selected antimicrobial medication consumption in inpatient units at North West Region Hospitals, Ministry of Health, Saudi Arabia. To increase the awareness of antimicrobial medication consumption side effect. Methods: It is a 9-month study about antimicrobial drug use by inpatients at North West region hospitals. It included inpatient department for adults, pediatrics and neonates. The medications were selected by Central Antibiotics committee at MOH as part of the National Antimicrobial Stewardship program. The consumption is driven from pharmacy database and calculated based on off-stranded unit of antimicrobial per hospital. The antimicrobials consisted of antibacterial drugs, antifungal and antiviral medications. The cost of antimicrobial consumption was calculated by using Ministry of Health National Cost database. All cost used as US currency. Results: The total number of Antimicrobial standard units was (25,845) and average (5,169) per hospital. The highest drug consumption was Ceftriaxone 1 gm injection (3,712) followed by Ceftazidime 1 gm injection (1807) and Gentamicin IV 80 mg (1,011) at adult{\textquoteright}s inpatient wards. The total cost of Antimicrobial consumption was (6,829,003.42 USD) and (1,365,800.68 USD) per hospital. The highest cost medication consumption from Adults inpatient departments was 99.62\% (6,803,229.92 USD) followed by pediatrics inpatient 0.24\% (16,087.6 USD) and Neonatal inpatient departments 0.14\% (9,685.9 USD). The highest medication cost was for very broad-spectrum antibiotics like Meropenem, Imipenem and Ceftriaxone. It consumed more than 50\% of the cost burden. Conclusion: There was very high consumption of antimicrobial drugs inpatient department with huge cost burden. Urgent application of antimicrobial stewardship program especially adults{\textquoteright} inpatients departments is a mandate and urgent.

}, keywords = {Antimicrobial, Consumption, Hospitals, Inpatient, Medications, Ministry of Health, North West (Tabuk), Saudi Arabia}, doi = {10.5530/PTB.2019.5.24}, author = {Abeer Hussin Almasoudi and Yousef Ahmed Alomi and Ghormallah Abdullah Alghamdi and Rasha Saad Alshahrani} } @article {135, title = {Antimicrobial Drug Consumption in Ambulatory Care Settings, Tabuk Region, Saudi Arabia}, journal = {Pharmacology, Toxicology and Biomedical Reports}, volume = {5}, year = {2019}, month = {August 2019}, pages = {97-101}, type = {Research Article}, chapter = {97}, abstract = {

Objectives: During the 21st century, Antimicrobial Resistance (AMR) has emerged as one of the principal public health problems worldwide. In the coming 20 years, health care systems may be incapable to treat bacterial diseases proficiently due to this miracle. We analyzed data from the North West Region Hospitals, Ministry of Health, Saudi Arabia to determine the level of knowledge regarding drug consumption among patients attending five hospitals in ambulatory care settings. Methods: This cross-sectional study was conducted at North West Region Hospitals in Tabuk city, Saudi Arabia for 9 months. The study contestants were selected from different outpatient departments. National Antimicrobial stewardship program highly demand at our country because of poor insight of antibiotics and misappropriation of antibiotics and poor adherence of antibiotics guidelines. Antibiotic consumption is driven from pharmacy database and calculated based on stranded unit of antimicrobial per each hospital. The total cost expenditure of antimicrobial drug consumption was calculated by Ministry of Health National Cost database. The predictable cost expressed in USD. All data and variables analyzed by Microsoft Excel program version 10. Results: The number of antimicrobial drug consumption in ambulatory care settings in the Saudi Arabia were 25,116 i.e. average 5,023.2 per hospital respectively. The highest drug consumption at all ambulatory care visits were azithromycin tablet (10,932), followed by azithromycin syrup (7,760) and moxifloxacin tablet (3218). The overall antimicrobial consumption was 37,620.12 USD and 7,524.02 USD per each hospital. The overall cost medication consumption were adults ambulatory care departments 69.42\% (26,114.79 USD), followed by pediatrics ambulatory care departments 24.52\% (9,226.018 USD) and neonates ambulatory care departments 6.06\% (2,279.32 USD). The highest medication cost was very broad-spectrum antibiotics like Levofloxacin, Linezolid PO IV and Moxifloxacin PO. It disbursed more than 50\% of the cost burden. Conclusion: Our results exposed a very high obliviousness of antimicrobial drug consumption and its contributing factors among the study contestants. Ambulatory care settings had a high consumption of antimicrobial drugs with burden cost. Thus, health education and responsiveness are highly and instantly suggested to address antimicrobial drug consumption and related resistances in the Tabuk area at ambulatory care settings. Antimicrobial stewardship program at Ambulatory care clinics is necessary to prevent bugs related resistance, improve patient outcome and avoid unnecessary cost on hospitals in Saudi Arabia.

}, keywords = {Ambulatory care clinics, Antimicrobial, Consumption, Hospitals, North West (Tabuk), Saudi Arabia}, doi = {10.5530/PTB.2019.5.18}, author = {Abeer Hussin Almasoudi and Yousef Ahmed Alomi and Ghormallah Abdullah Alghamdi} } @article {137, title = {Antimicrobial Drug Consumption in Emergency Services at North West (Tabuk) Region Hospitals, Saudi Arabia}, journal = {Pharmacology, Toxicology and Biomedical Reports}, volume = {5}, year = {2019}, month = {August 2019}, pages = {108-112}, type = {Research Article}, chapter = {108}, abstract = {

Objectives: This article describes antimicrobial medication use among different age groups and the cost associated with it in emergency department at Northern West (Tabuk) hospitals, Saudi Arabia. The aim of this study to declare the antimicrobial medication use in emergency Units at North West Region Hospitals, Ministry of Health, Saudi Arabia. Methods: It is a 12-month antimicrobial drug consumption by emergency services at North West region hospitals. It included all adults, pediatrics and neonatal population. The medications were selected by Central Antibiotics committee at MOH as part of the National Antimicrobial Stewardship program. The consumption is driven from pharmacy database and calculated based on off stranded unit of antimicrobial per hospital. The cost of antibiotics consumption was calculated by using Ministry of Health National Cost database. All cost used was as US currency. Results: The total number of Antimicrobial standard units at Emergency departments were (8,805.00) with average (1,761.00) per hospital. The highest general drug consumption was Azithromycin PO 200 mg/15 ml (4253) and Ceftriaxone IV 1 g (805) and Gentamicin IV 80 mg (401) at Emergency departments. The total cost of antimicrobial consumption was (24,822.60 USD) and (4,964.52 USD) per hospital. The highest cost medication consumption from Adults Emergency departments was 59.85\% (24,822.60 USD) followed by pediatrics Emergency departments 28.99\% (7,197.03 USD) and Neonates Emergency departments of 11.16\% (2,769.98 USD). The highest medication cost was for very broad-spectrum antibiotics like Meropenem IV, Azithromycin PO and Moxifloxacin IV. It consumed more than 60 \% of the cost burden. Conclusion: The Emergency department had a high consumption of antimicrobial drugs with burden cost. Antimicrobial stewardship program at Emergency services are necessary to prevent bugs related resistance, improve patient outcome and avoid necessary additional economic burden on healthcare system in the Kingdom of Saudi Arabia.

}, keywords = {Antimicrobial, Consumption, Emergency, Hospitals, North West (Tabuk), Saudi Arabia, Services}, doi = {10.5530/PTB.2019.5.20}, author = {Yousef Ahmed Alomi and Abeer Hussin Almasoudi and Ghormallah Abdullah Alghamdi and Nora Ali Abboud} }